Comparison 2. Antihypertensive drug therapy vs control according to subgroup (60 to 79 years old and 80 years or older).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Total mortality	11	25718	Risk Ratio (M‐H, Fixed, 95% CI)	0.90 [0.84, 0.97]
1.1 60 to 79 years old	9	19017	Risk Ratio (M‐H, Fixed, 95% CI)	0.86 [0.79, 0.95]
1.2 80 years or older	8	6701	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.87, 1.10]
2 Cardiovascular mortality and morbidity	10		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 60 to 79 years old	8	18484	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.65, 0.77]
2.2 80 years or older	7	6546	Risk Ratio (M‐H, Fixed, 95% CI)	0.75 [0.65, 0.87]
3 Cerebrovascular mortality and morbidity	10		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 60 to 79 years old	8	18484	Risk Ratio (M‐H, Fixed, 95% CI)	0.66 [0.58, 0.76]
3.2 80 years or older	7	6546	Risk Ratio (M‐H, Fixed, 95% CI)	0.66 [0.52, 0.83]
4 Coronary heart disease mortality and morbidity	8		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 60 to 79 years old	7	18284	Risk Ratio (M‐H, Fixed, 95% CI)	0.79 [0.69, 0.90]
4.2 80 years or older	6	5263	Risk Ratio (M‐H, Fixed, 95% CI)	0.82 [0.56, 1.20]