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. 2019 Jun 5;2019(6):CD000028. doi: 10.1002/14651858.CD000028.pub3
Date Event Description
6 June 2018 New search has been performed Search has been updated until 24 November 2017
One new study has been added to this update: MRC‐TMH 1985
Included studies have been identified using the same names as used in the "First line drugs for hypertension" (Wright 2018) and "Pharmacotherapy for hypertension in adults 18 to 59 years" (Musini 2017) Cochrane Reviews
The definition of cardiovascular mortality and morbidity outcome was modified in this update in keeping with the definition used in the 2 similar reviews mentioned above; the revised outcome does not include transient ischaemic attacks. However, when it was not possible to exclude transient ischaemic attacks from the outcome in some studies, we reported the overall effect size while including these studies and while deselecting them
Risk of bias of all studies has been assessed. Overall grading of evidence for adults 60 years or older is documented in a "Summary of findings" table
In the "Additional tables" section, overall grading of evidence is provided separately for the age groups 60 to 79 years and 80 years or older
6 June 2018 New citation required but conclusions have not changed The title of the review has been changed from "Pharmacotherapy for hypertension in elderly" to "Pharmacotherapy for hypertension in adults 60 years or older". Numerous changes were made to methods and reporting
27 October 2009 Amended Corrected denominator of the STOP trial for total mortality from 22 to 122 in the hypertension in the very elderly subgroup
11 August 2009 New citation required and conclusions have changed Prepared substantive update; review authors and conclusions have changed
11 August 2009 Feedback has been incorporated Excluded HDFP trial because it is a multi‐interventional study
28 October 2008 Feedback has been incorporated New feedback received 28 October 2008
13 August 2008 Amended Converted to new review format
5 June 2006 Amended Minor update prepared
17 November 2004 Feedback has been incorporated Feedback added