Skip to main content
. 2019 Jun 5;5(6):eaaw7396. doi: 10.1126/sciadv.aaw7396

Fig. 2. Creation of cross-linked, biofunctionalized hydrogels.

Fig. 2

(A) Synthesis of PdBT cross-linker. THF, tetrahydrofuran; RT, room temperature. (B) Generation of biofunctionalized cross-linkers by mixing PdBT with tissue-specific biomolecules in water at room temperature in the presence of catalyst and disulfide inhibitor. (C) Spontaneous chemical cross-linking and physical gelation of a model P(NIPAAm-co-GMA) system induced by mixing the polymer with biofunctionalized PdBT in phosphate-buffered saline (PBS) (pH 7.4) at 37°C.