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. Author manuscript; available in PMC: 2019 Jun 5.
Published in final edited form as: J Biomed Mater Res A. 2019 Jan 23;107(4):884–892. doi: 10.1002/jbm.a.36605

FIGURE 5.

FIGURE 5.

Decreasing pore size of 140 mg/mL electrospun scaffolds has little effect on IL-6 and TNF production. (A) Fiber and pore diameters of the indicated scaffolds were calculated from SEM images. Fiber diameter was calculated from 25 to 40 measures; pore diameter is from 60 measurements. (B) Representative electromicrograph of a 140C scaffold. (C) BMMC were seeded on fibronectin-coated 140 and 140C electrospun scaffolds for 48 h and then activated with LPS (1 μg/mL) or IL-33 (100 ng/mL). Supernatants were collected 16 h later and analyzed via ELISA for IL-6 and TNF. Results are presented as mean ± SEM of nine samples from three independent experiments. *, p < 0.05; **, p < 0.01; ****, p < 0.0001; NS, not significant.