Table 1. Summary of participant characteristics (Mean ± SD) or Median (Quartiles).
| Variable | Controls (n = 25) | SCA6 |
|
|---|---|---|---|
| SCA6Pre n = 6 | SCA6Clin n = 18 | ||
| Age (years) | 50.2 ± 12.2 | 42.33 ± 14.6 | 61.5 ± 8.5 * ƚ |
| Sex | f 17, m 8 | f 4, m 2 | f 13, m 5 |
| Falls history | (0/25) | (1/6) | (4/18) |
| Height (m) | 1.67 ± .09 | 1.67 ± .09 | 1.65 ± .08 |
| Body mass (kg) | 74.1 ± 13.7 | 71.6 ± 15.5 | 78.8 ± 12.5 |
| Body mass index | 26.6 ± 4.6 | 24.6 ± 2.9 | 28.6 ± 3.7 † |
| Disease Duration | - | - | 3.7 ± 3.2 |
| ABCS (0-100) | 96.0 ± 3.7 | 86.3 ± 8.1 * | 59.2 ± 24.3 * † |
| ICARS (0-100) | |||
| Total | 3 (1, 3) | 20.5 (13.75, 20.5) † | |
| Gait and Posture | 1 (.75, 1) | 7.5 (6, 7.5) † | |
| Kinetic | 0 (0, 0) | 6 (4, 6) † | |
| Speech and Language | 0 (0, 0) | 1 (0, 1) † | |
| Oculomotor | 0.5 (0, 0.5) | 2.5 (2, 2.5) † | |
*
= significant difference from controls (p <.05)
ƚ
= significant difference from SCA6Pre (p <.05)