Table 1. tHcy, homocystine and Met concentrations at diagnosis and under treatment.
| Parameter units and reference ranges | At diagnosis | Under treatment | ||||
|---|---|---|---|---|---|---|
| Median (range) | Mean | n | Median (range) | Mean | n | |
| Plasma tHcy (5-15 µmol/L) |
170 (30-316) |
163 | 28 | 71(23-127) | 73 | 29 |
| Free homocystine (µmol/L) Normally undetectable |
29 (9-70) |
32 | 14 | 3.1(0.6-14) | 5.7 | 8 |
| Urine homocystine (µmol/ mmol creatinine) Normally undetectable) |
29 (4-627) |
113 | 13 | - | - | 3 |
| Plasma methionine (10-39 µmol/L) |
9 (0-29) |
9 | 30 | 27 (11-89) | 35 | 23 |