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. Author manuscript; available in PMC: 2019 Jun 5.
Published in final edited form as: Hum Reprod. 2018 Jul 1;33(7):1331–1341. doi: 10.1093/humrep/dey114

Table 3. Maximum likelihood estimates (MLE) for the standard (H0) and truncated (H1) Kimura models. Bold indicated the hypothesis that is most likely based on the Akaike information criterion (AIC).

carrier Fit p0 b Truncation (%) Neff AIC
[95% CI]
m.3243A>G #1 H0 0.41 0.80     66.5       [50-86] 2.0
H1 0.41 0.87 67.4    110.8     [90-151] -11.4
m.3243A>G #2 H0 0.34 0.85      94.4      [45-133] -6.1
H1 0.34 0.88 65.1    113.3     [71-172] -7.0
m.3243A>G #3 H0 0.39 0.73     47.8       [23-68] 8.7
H1 0.40 0.85 71.5      90.4      [67-127] 3.3
m.3243A>G #4 H0 0.33 0.86      97.0      [54-127] -13.5
H1 0.33 0.86 76.5   102.3     [64-149] -12.2
m.3243A>G #5 H0 0.16 0.91   162.3     [64-352] -13.2
H1 0.16 0.95 32.4    265.9    [180-447] -14.5
All m.3243A>G H0 0.35 0.81     71.2      [53-93] -20.7
H1 0.35 0.84 76.5    83.3      [74-96] -26.6
m.8993T>G H0 0.05 0.36   14.5       [7-27] 37.1
m.14487T>C H0 0.64 0.68    39.0      [25-48] 8.9