Table 2.

Comparison of the four tools on different insert size data

Methods	Insert size
	180	2283 to 2803	Combined
GAPPadder	862	1481	1670
GapCloser	1142	216	1184
GapFiller	484	173	732
Sealer	468	308	559

Three groups of data of insert sizes (180, about 2500 and about 35 kb) of human chromosome 14, and their combination are used for comparison. Results are given for reads with 180 bp insert size only, and reads with 2500 bp insert size only and combined reads (with 180 bp, 2500 bp and 35 kb insert sizes)