Figure 6.
Results from the network based statistics comparison of fiber density and co-classification (pFDR < 0.05). (A) Higher fiber density in alcohol use disorder (AUD) subjects compared to controls (CON) was found between nodes located in the middle frontal and superior frontal gyri. (B) Co-classification index (measure of strength of association of a pair of nodes in an ensemble of community structure partitions obtained from modularity), was higher in AUD compared to CON in edges that connect middle frontal gyrus and pre/postcentral gyrus (left) node pairs, cuneus and middle temporal gyrus (right), and supplementary motor area and middle occipital gyrus (right). (C) One edge that connected nodes in the cuneus and inferior insula showed lower co-classification in AUD compared to CON. Renders are on a Montreal Neurological Institute 1mm template included in FSL, visualized with MRIcroGL software. Node pairs with edges that differed between groups are overlaid in shaded gray. A black line was used to specify the connected pair, when multiple pairs are presented on a single underlay. R and L represent right and left hemisphere, respectively.