Table 3.
Associations of biomarker concentrations with HIV status, demographics, smoking and alcohol use in the full sample
| B | 95% CI | p-value | |
|---|---|---|---|
| LBP (ng/ml) | |||
| HIV infectiona | 4304.9 | 1293.3, 7316.4 | .005 |
| Sexb | 5574.2 | 2250.6, 8897.8 | .001 |
| Age | 66.8 | −61.7, 195.2 | .308 |
| Cigarettes/day | 209.1 | 3.7, 414.5 | .046 |
| Current alcohol usec | . | ||
| Moderate drinking | −30.3 | −3089.6, 3029.0 | .985 |
| Heavy drinking | −1771.0 | −5960.1, 2418.2 | .407 |
| LPS (pg/ml, log10 transformed) | |||
| HIV infection | .123 | .025, .221 | .014 |
| Sex | .085 | -.008, .179 | .072 |
| Age | −.006 | -.009, −.002 | .002 |
| Cigarettes/day | −.002 | -.007, .003 | .364 |
| Current alcohol use | |||
| Moderate drinking | −.025 | -.134, .083 | .647 |
| Heavy drinking | −.010 | -.137, .116 | .871 |
| sCD14 (ng/ml) | |||
| HIV infection | 538.1 | 349.0, 727.3 | < .001 |
| Sex | 298.9 | 103.6, 494.2 | .003 |
| Age | 2.7 | -7.2, 12.5 | .598 |
| Cigarettes/day | 4.5 | -8.0, 17.0 | .482 |
| Current alcohol use | |||
| Moderate drinking | −26.3 | -238.5, 185.9 | .808 |
| Heavy drinking | −128.1 | -408.2, 152.0 | .370 |
| sCD163 (ng/ml) | |||
| HIV infection | 237.8 | 109.8, 365.8 | < .001 |
| Sex | 118.0 | −8.3, 244.3 | .067 |
| Age | 1.1 | −4.5, 6.8 | .693 |
| Cigarettes/day | −12.4 | −27.4, 2.5 | .103 |
| Current alcohol use | |||
| Moderate drinking | 29.3 | −281.4, 340.0 | .853 |
| Heavy drinking | 103.2 | −166.0, 372.5 | .452 |
Coded to indicate biomarker values in HIV-infected participants relative to uninfected participants.
Coded to indicate biomarker values in women relative to men.
Comparisons are to non-drinking group.