Table 1.
Study Participant Demographics
| Age of recipient, years, median (25%Q, 75%Q) | 50 (40, 58) |
| Race/ethnicity, n (%) | |
| Black or African American | 4 (11) |
| Hispanic or Latino | 7 (18) |
| White or Caucasian | 25 (66) |
| Unidentified | 2 (5) |
| Female sex, n (%) | 32 (84) |
| Previous renal transplant, n (%) | 9 (24) |
| Presence of 2nd organ transplant, n (%) | 13 (34) |
| Neurogenic bladder, n (%) | 2 (5) |
| Primary etiology of end stage renal disease, n (%) | |
| Diabetic nephropathy | 18 (47) |
| Hypertensive nephrosclerosis | 3 (8) |
| Graft failure | 4 (11) |
| Nonalcoholic steatohepatitis | 2 (5) |
| Systemic Lupus Erythematosus | 2 (5) |
| Chronic glomerulonephritis | 2 (5) |
| Other | 7 (18) |
| GFR pre-methenamine | |
| >60 ml/min/1.73m2, n (%) | 11 (29) |
| <60 ml/min/1.73m2, n (%) | 27 (71) |
| <60 ml/min/1.73m2, median ml/min (minimum ml/min) | 45 (21) |
| GFR post-methenamine | |
| >60 ml/min/1.73m2, n (%) | 12 (32) |
| <60 ml/min/1.73m2, n (%) | 26 (68) |
| <60 ml/min/1.73m2, median ml/min (minimum ml/min) | 41 (17) |
| Follow-up days pre-methenamine | |
| Total for all patients, thousand days | 12.1 |
| Individual patients, median (25%Q, 75%Q) | 365 (299, 365) |
| Follow-up days post-methenamine | |
| Total for all patients, thousand days | 9.8 |
| Individual patients, median (25%Q, 75%Q) | 314 (105, 365) |
| Days from transplant to methenamine start, median (25%Q, 75%Q) | 1192 (300, 2433) |
| Total days of methenamine treatment, median (25%Q, 75%Q) | 314 (105, 566) |
| Immunosuppressive regimen, n (%) | |
| Mycophenolic acid | 35 (92) |
| Tacrolimus | 26 (68) |
| Sirolimus | 4 (11) |
| Prednisone | 9 (24) |
| Azathioprine | 2 (5) |
| Cyclosporine | 3 (8) |