Table 1.
Study Participant Demographics
Age of recipient, years, median (25%Q, 75%Q) | 50 (40, 58) |
Race/ethnicity, n (%) | |
Black or African American | 4 (11) |
Hispanic or Latino | 7 (18) |
White or Caucasian | 25 (66) |
Unidentified | 2 (5) |
Female sex, n (%) | 32 (84) |
Previous renal transplant, n (%) | 9 (24) |
Presence of 2nd organ transplant, n (%) | 13 (34) |
Neurogenic bladder, n (%) | 2 (5) |
Primary etiology of end stage renal disease, n (%) | |
Diabetic nephropathy | 18 (47) |
Hypertensive nephrosclerosis | 3 (8) |
Graft failure | 4 (11) |
Nonalcoholic steatohepatitis | 2 (5) |
Systemic Lupus Erythematosus | 2 (5) |
Chronic glomerulonephritis | 2 (5) |
Other | 7 (18) |
GFR pre-methenamine | |
>60 ml/min/1.73m2, n (%) | 11 (29) |
<60 ml/min/1.73m2, n (%) | 27 (71) |
<60 ml/min/1.73m2, median ml/min (minimum ml/min) | 45 (21) |
GFR post-methenamine | |
>60 ml/min/1.73m2, n (%) | 12 (32) |
<60 ml/min/1.73m2, n (%) | 26 (68) |
<60 ml/min/1.73m2, median ml/min (minimum ml/min) | 41 (17) |
Follow-up days pre-methenamine | |
Total for all patients, thousand days | 12.1 |
Individual patients, median (25%Q, 75%Q) | 365 (299, 365) |
Follow-up days post-methenamine | |
Total for all patients, thousand days | 9.8 |
Individual patients, median (25%Q, 75%Q) | 314 (105, 365) |
Days from transplant to methenamine start, median (25%Q, 75%Q) | 1192 (300, 2433) |
Total days of methenamine treatment, median (25%Q, 75%Q) | 314 (105, 566) |
Immunosuppressive regimen, n (%) | |
Mycophenolic acid | 35 (92) |
Tacrolimus | 26 (68) |
Sirolimus | 4 (11) |
Prednisone | 9 (24) |
Azathioprine | 2 (5) |
Cyclosporine | 3 (8) |