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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: DNA Repair (Amst). 2019 Apr 27;79:1–9. doi: 10.1016/j.dnarep.2019.04.006

Figure 3.

Figure 3.

Bleomycin-induced transformation affects genome-wide expression and methylation. (A) Venn diagram summarizing common and unique genes with differential expression fold change ≥50% in HBEC pSil Bleo-T and HBEC DNA-PKc Bleo-T cells compared to vehicle controls. (B) Common major pathways significantly altered in response to gene expression changes across transformed cell lines are ranked by −1 × log10 P values. (C) Pathways altered in p-Sil Bleo-T cells. (D) Pathways altered in DNA-PKc Bleo-T cells. (E) Venn diagram summarizing common and unique methylated genes in HBEC pSil Bleo-T and HBEC DNA-PKc Bleo-T cells compared to vehicle controls.