Fig. 1.
Alterations in the amplitude of low-frequency fluctuation (ALFF) in the chemotherapy group from pre- (time point 1, TP1) to post-chemotherapy (time point 2, TP2). The highlighted area is a single cluster showing a statistically significant increase in ALFF from TP1 to TP2 (p-corrected < 0.05). This cluster includes parts of the right subcallosal gyrus (8, 16, −16), left subcallosal gyrus (−8, 14, −14) and right anterior cingulate gyrus (4, 22, −8; Brodmann 32). The color bar in the right lower panel indicates the scale of the t statistics for the within-group comparison of ALFF between the TP1 and TP2.