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No effect of single administration of nalfurafine (10ug/kg) on locomotor activity in alcohol-naïve male and female mice. Locomotor activity is assessed as the number of “crossings,” defined as breaking the light beams at either end of the conditioning chamber. Data in table are presented as mean ± SEM.
| Sex | Male (n = 6) | Female (n = 6) | ||
|---|---|---|---|---|
| Treatment | vehicle | 10 ug/kg | vehicle | 10 ug/kg |
| Crossings (30 min) | 228 ± 60 | 199 ± 48 | 268 ± 55 | 251 ± 42 |
