Table 5.
No effect of single nalfurafine (10ug/kg) on conditioned place aversion (CPA) in alcohol-naïve male and female mice. The time spent in either the nalfurafine-paired compartment or the vehicle (saline)-paired compartment was recorded for 30 min in both the preconditioning session and CPA test for 30 min. Data in table are presented as mean ± SEM.
Sex | Male (n = 6) | Female (n = 6) | ||
---|---|---|---|---|
Treatment | vehicle | 10ug/kg | vehicle | 10ug/kg |
Preconditioning: time spent in chambers (sec) | 462 ± 49 | 477 ± 60 | 431 ± 55 | 429 ± 61 |
CPA test: time spent in chambers (sec) | 438 ± 52 | 420 ± 46 | 452 ± 45 | 449 ± 69 |