Table 1.
Demographic and clinical data of participants
| Variables | MDD (N = 25) |
MDD-Medicated (N = 19) |
HC (N = 28) |
MDD vs. HC | MDD-Medicated vs. HC | |||
|---|---|---|---|---|---|---|---|---|
| Mean | (SD) | Mean | (SD) | Mean | (SD) | P* | P* | |
| Ages(years) | 36.6 | 12.8 | 36.2 | 12.8 | 34.3 | 12.4 | NS | NS |
| Sex | 15 (60%) men | 12 (63.2%) men | 15 (53.6%) men | NS# | NS# | |||
| HAMD | 18.2 | 6.4 | 18.1 | 6.3 | 0.8 | 1.4 | <0.001 | <0.001 |
| TSD(years) | 6.4 | 6.0 | 7.2 | 6.5 | 0 | 0 | <0.001 | <0.001 |
| THV(mm3) | 8798.2 | 2710.5 | 8998.4 | 2704.3 | 9863.1 | 1743.8 | NS | NS |
| LHV(mm3) | 4303.5 | 1687.2 | 4280.8 | 1472.4 | 4701.4 | 991.6 | NS | NS |
| RHV(mm) | 4494.7 | 1351.2 | 4717.6 | 1337.3 | 5161.7 | 926.6 | NS | NS |
| TAV(mm) | 2453.3 | 1023.1 | 2702.4 | 1006.9 | 2916.1 | 702.8 | NS | NS |
| LAV(mm) | 1247.7 | 540.7 | 1388.5 | 530.9 | 1405.3 | 349.9 | NS | NS |
| RAV(mm) | 1205.6 | 583.9 | 1313.9 | 589.1 | 1510.7 | 511.3 | 0.048 | NS |
SD Standard Deviation, NS Not Significant, TSD Time Since Diagnosis, THV Total Hippocampus Volume, LHV Left Hippocampus Volume, RHV Right Hippocampus Volume, TAV Total Amygdala Volume, LAV Left Amygdala Volume, RAV Right Amygdala Volume
p*
Student’s t-test for independent samples
NS#
χ2 test