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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Curr Med Chem. 2020;27(21):3412–3447. doi: 10.2174/0929867325666181120101147

Figure 11.

Figure 11

The chemical structures of sulfated NSGMs (3842) that inhibited angiogenesis in an in vitro tube formation assay. Minimal ‘pharmacophore’ appears to be two sulfate groups at an optimal distance of 5–10 Å.