Reexpression of HNF4α restores hepatocyte quiescence and gene expression and extends survival of HNF4α-KO animals post-PH. (A) Western blot analysis of HNF4α, Cyclin D1, c-Met and EGFR in WT, HNF4α-KO and HNF4α-Reexp. mice, (B) Immunohistochemical analysis of PCNA positive nuclei in liver sections from WT, HNF4α-KO and HNF4α-Reexp. mice, (C) Representative photomicrographs (40x) of PCNA-stained liver sections, (D) Kaplan-Meier survival analysis of WT and HNF4α-Reexp mice after PH. * indicate significant difference at P ≤ 0.05.