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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Hepatology. 2019 Mar 10;70(2):666–681. doi: 10.1002/hep.30405

Table 2:

Predicted Activity of Transcription Factors in HNF4α-KO Mice Compared to WT Mice 5 Days Post-PH.

Day 5 Post-PH
Activated Pathways Activation z-score Inhibited Pathways Activation z-score
Gm21596/Hmgb1 2.767 HNF4A −6.471
EP300 2.565 HNF1A −4.641
TRIM24 2.554 SREBF2 −4.603
SMAD2 2.401 SREBF1 −3.768
CCND1 2.307 PPARGC1A −3.045
SNAI2 2.1 Esrra −2.887
ANKRD42 2 IRF7 −2.476
PLAG1 2 SIRT2 −2.449
NFIX −2.433
PPARGC1B −2.424
BCL6 −2.229
EBF1 −2.177
ZEB1 −2.077
NCOA2 −2.028