Fig. 1. ZNF384 is frequently up-regulated in hepatocellular carcinoma (HCC) and associated with recurrence and poor prognosis of HCC patients.
a The alter frequency and the expression changes of ZNF384 in HCC from TCGA database. b Upregulated ZNF384 mRNA expression in HCC compared with normal liver tissue in TCGA database. c Immunohistochemical staining of ZNF384 protein expression in 71 pairs of clinical HCC and adjacent noncancerous tissues. d Difference in IHC score of ZNF384 protein between HCC and adjacent noncancerous tissues. e Kaplan–Meier analysis showing that the expression level of ZNF384 in 71 HCC patient samples is significantly associated with poorer overall survival (log-rank test). f Kaplan–Meier analysis showing that the expression level of ZNF384 in 71 HCC patient samples is significantly associated with tumor-free survival (log-rank test)