Fig. 4.

MiR-499-5p overexpression played an anti-apoptosis role. a, b Apoptosis was detected in control, hypoxia, mock + hypoxia, mimic + hypoxia, mimic + SOX6 + hypoxia and mimic + NC + hypoxia group by flow cytometry. (C-F) The levels of Bcl-2, Bax and caspase-3 were determined in control, hypoxia, mock + hypoxia, mimic + hypoxia, mimic + SOX6 + hypoxia and mimic + NC + hypoxia group by western blot. GAPDH was as an internal reference. ^**P < 0.01 vs. control, ^&&P < 0.01 vs. hypoxia, ^@@P < 0.01 vs. mimic + hypoxia