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. 2019 Jun;6(6):506–517. doi: 10.1016/S2215-0366(19)30126-9

Table 1.

Demographic composition, deaths, and crude mortality rates in the sample

Total sample All-cause mortality
Natural cause mortality
Unnatural cause mortality
All-cause deaths Crude rate (95% CI) Natural-cause deaths Crude rate (95% CI) Unnatural-cause deaths Crude rate (95% CI)
Total 18 201 (100%) 1767 (9·7%) 14·4 (13·7–15·1) 1417 (7·8%) 11·5 (11·0–12·2) 192 (1·1%) 1·6 (1·4–1·8)
Area level indicators
Index of Multiple Deprivation (rank score)
4 (most deprived) 3667 (20·1%) 377 (10·3%) 14·4 (13·0–16·0) 305 (8·3%) 11·7 (10·4–13·1) 33 (0·9%) 1·3 (0·9–1·8)
4276 3646 (20·0%) 342 (9·4%) 13·3 (12·0–14·8) 273 (7·5%) 10·6 (9·4–12·0) 35 (1·0%) 1·4 (1·0–1·9)
6144 3629 (19·9%) 313 (8·6%) 12·5 (11·2–14·0) 247 (6·8%) 9·9 (8·7–11·2) 37 (1·0%) 1·5 (1·1–2·0)
8747 3673 (20·2%) 371 (10·1%) 14·9 (13·5–16·5) 297 (8·1%) 12·0 (10·7–13·4) 39 (1·1%) 1·6 (1·1–2·1)
12 859 (least deprived) 3586 (19·7%) 364 (10·2%) 17·3 (15·6–19·2) 295 (8·2%) 14·0 (12·5–15·7) 48 (1·3%) 2·3 (1·7–3·0)
Urbanicity (persons per hectare)
0·1 (least populous) 3613 (19·9%) 377 (10·4%) 17·5 (15·8–19·4) 301 (8·3%) 14·0 (12·5–15·7) 42 (1·2%) 2·0 (1·4–2·6)
55·3 3762 (20·7%) 370 (9·8%) 15·0 (13·5–16·6) 282 (7·5%) 11·4 (10·2–12·8) 49 (1·3%) 2·0 (1·5–2·6)
88·6 3667 (20·1%) 347 (9·5%) 13·5 (12·1–14·9) 275 (7·5%) 10·7 (9·5–12·0) 41 (1·1%) 1·6 (1·2–2·2)
111·4 3652 (20·1%) 374 (10·2%) 14·7 (13·3–16·2) 315 (8·6%) 12·4 (11·1–13·8) 29 (0·8%) 1·1 (0·8–1·6)
145·0 (most populous) 3507 (19·3%) 299 (8·5%) 11·8 (10·6–13·3) 244 (7·0%) 9·7 (8·5–11·0) 31 (0·9%) 1·2 (0·9–1·7)
Social fragmentation
−7·2 (least fragmented) 4669 (25·7%) 451 (9·7%) 15·8 (14·4–17·3) 364 (7·8%) 12·7 (11·5–14·1) 51 (1·1%) 1·8 (1·4–2·3)
−2·4 4593 (25·2%) 477 (10·4%) 15·0 (13·7–16·4) 390 (8·5%) 12·3 (11·1–13·6) 45 (1·0%) 1·4 (1·1–1·9)
−0·2 4534 (24·9%) 469 (10·3%) 14·7 (13·4–16·1) 366 (8·1%) 11·5 (10·4–12·7) 52 (1·1%) 1·6 (1·2–2·1)
2·0 2686 (14·8%) 227 (8·5%) 12·2 (10·7–13·9) 185 (6·9%) 9·9 (8·6–11·5) 25 (0·9%) 1·3 (0·9–2·0)
>4·7 (most fragmented) 1719 (9·4%) 143 (8·3%) 12·1 (10·3–14·3) 112 (6·5%) 9·5 (7·9–11·4) 19 (1·1%) 1·6 (1·0–2·5)
Ethnic density (% ethnic minorities)
0·3 (lowest ethnic density) 1665 (9·1%) 138 (8·3%) 16·6 (14·0–19·7) 107 (6·4%) 12·9 (10·7–15·6) 23 (1·4%) 2·8 (1·8–4·2)
19·0 1783 (9·8%) 189 (10·6%) 16·3 (14·1–18·8) 154 (8·6%) 13·3 (11·3–15·5) 21 (1·2%) 1·8 (1·2–2·8)
28·7 1788 (9·8%) 187 (10·5%) 15·2 (13·2–17·6) 152 (8·5%) 12·4 (10·6–14·5) 20 (1·1%) 1·6 (1·1–2·5)
35·0 1765 (9·7%) 173 (9·8%) 13·8 (11·8–16·0) 135 (7·6%) 10·7 (9·1–12·7) 19 (1·1%) 1·5 (1·0–2·4)
39·6 1861 (10·2%) 171 (9·2%) 13·2 (11·4–15·4) 135 (7·3%) 10·5 (8·8–12·4) 24 (1·3%) 1·9 (1·2–2·8)
43·8 1851 (10·2%) 208 (11·2%) 16·0 (14·0–18·3) 166 (9·0%) 12·8 (11·0–14·9) 22 (1·2%) 1·7 (1·1–2·6)
48·4 1840 (10·1%) 190 (10·3%) 14·6 (12·7–16·8) 149 (8·1%) 11·5 (9·8–13·5) 15 (0·8%) 1·2 (0·7–1·9)
53·3 1884 (10·4%) 181 (9·6%) 13·5 (11·7–15·6) 146 (7·7%) 10·9 (9·3–12·8) 18 (1·0%) 1·3 (0·8–2·1)
60·0 1872 (10·3%) 162 (8·7%) 12·5 (10·8–14·6) 137 (7·3%) 10·6 (9·0–12·5) 11 (0·6%) 0·9 (0·5–1·5)
67·1 (highest ethnic density) 1892 (10·4%) 168 (8·9%) 13·2 (11·3–15·4) 136 (7·2%) 10·7 (9·0–12·6) 19 (1·0%) 1·5 (1·0–2·3)
Individual-level indicators
Age at diagnosis (years)*
<38·1 8723 (47·9%) 230 (2·6%) 3·92 (3·4–4·5) 121 (1·4%) 2·1 (1·7–2·5) 92 (1·1%) 1·6 (1·3–1·9)
≥38·2 9478 (52·1%) 1537 (16·2%) 24·0 (22·8–25·2) 1296 (13·7%) 20·2 (19·2–21·4) 100 (1·1%) 1·6 (1·3–1·9)
Gender
Males 9610 (52·8%) 908 (9·4%) 13·4 (12·6–14·3) 707 (7·4%) 10·4 (9·7–11·2) 132 (1·4%) 1·9 (1·6–2·3)
Females 8591 (47·2%) 859 (10·0%) 15·6 (14·6–16·7) 710 (8·3%) 12·9 (12·0–13·9) 60 (0·7%) 1·1 (0·8–1·4)
Diagnosis
Non-affective 13 160 (72·3%) 1358 (10·3%) 14·7 (14·0–15·5) 1090 (8·3%) 11·8 (11·1–12·5) 141 (1·1%) 1·5 (1·3–1·8)
Affective 5041 (27·7%) 409 (8·1%) 13·4 (12·2–14·8) 327 (6·5%) 10·7 (9·6–11·9) 51 (1·0%) 1·7 (1·3–2·2)
Marital status
Married or cohabiting 2781 (15·3%) 267 (9·6%) 15·8 (14·0–17·8) 220 (7·9%) 13·0 (11·4–14·9) 22 (0·8%) 1·3 (0·9–2·0)
Divorced, separated, widowed, or single 15 420 (84·7%) 1500 (9·7%) 14·2 (13·5–14·9) 1197 (7·8%) 11·3 (10·7–12·0) 170 (1·1%) 1·6 (1·4–1·9)
Substance use disorder
No substance use disorder 15 046 (82·7%) 1519 (10·1%) 15·1 (14·3–15·8) 1251 (8·3%) 12·4 (11·7–13·1) 128 (0·9%) 1·3 (1·1–1·5)
Life-time substance use disorder 3155 (17·3%) 248 (7·9%) 11·3 (10·0–12·9) 166 (5·3%) 7·6 (6·5–8·8) 64 (2·0%) 2·9 (2·3–3·7)
Ethnicity
White British 9047 (49·7%) 1130 (12·5%) 19·9 (18·8–21·1) 913 (10·1%) 16·1 (15·1–17·2) 125 (1·4%) 2·2 (1·8–2·6)
Ethnic minorities 9154 (50·3%) 637 (7·0%) 9·7 (8·9–10·4) 504 (5·5%) 7·6 (7·0–8·3) 67 (0·7%) 1·0 (0·8–1·3)

Data are n (%), unless otherwise specified. Crude rates are per 1000 person-years. 158 deaths were from causes not otherwise classified (R00-R99) and contribute to all-cause mortality totals in the sample.

*

Age was handled as a time-varying covariate in all regression models and is displayed here divided at the median.