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. 2019 Jun 4;21(7):721–729. doi: 10.1016/j.neo.2019.04.009

Figure 4.

Figure 4

RASL11A (A) Box plot of relative RASL11A expression levels in 8 aneuploid and 6 diploid CRC cell lines. The x-axis depicts the two groups while the y-axis depicts the relative expression level of RASL11A. (B) RASL11A relative expression in the transduced DLD-1 WT, clone 13–2 and clone 13–3 normalized to the empty vector (EV) controls. (C) Western blot for RASL11A and the loading control, β-actin for DLD-1 WT with RASL11A overexpression and DLD-1 + 13 clone 13–2 with RASL11A overexpression. RASL11A expression was induced by doxycycline in the indicated concentration. (D) Seven-day growth curve of DLD-1 + 13 clone 13–2 empty vector (EV) and RASL11A. (E) Box plot of the number of colonies (y-axis) in DLD-1 + 13 clone 13–3 EV control and RASL11A overexpression. *P ≤ .05. (F) Scratch assay between DLD-1 WT cells and DLD-1 + 13 clone 13–3 cells. Each compares EV vs RASL11A overexpression. *P ≤ .05, N.S. = P > .05.