Table 1.
Outcome definitions
| Clinical outcome | Cause of death | Hospitalizations |
|
|---|---|---|---|
| Diagnosis | Procedure | ||
| (2) Fatal and nonfatal MI | Acute myocardial infarction | Acute myocardial infarction | Coronary angioplasty |
| Atherosclerotic heart disease | Cardiac arrest/sudden death | Coronary artery bypass graft | |
| (3) Fatal and nonfatal stroke | Stroke, hemorrhagic | TIA | |
| Stroke, ischemic | Stroke (CVA) | ||
| (4) Hospitalization for HF | Congestive heart failure | Congestive heart failure | |
| (5) Thromboembolic events, nonvascular access | Pulmonary embolus | Deep vein thrombosis | Arterial bypass surgery |
CVA, cardiovascular accident; MACE, major adverse cardiovascular events, defined as all-cause mortality or outcomes (2) and (3) above; MACE+, MACE plus heart failure and thromboembolic events (additionally includes outcomes [4] or [5]); TIA, transient ischemic attack.