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. 2019 May 31;14:4071–4090. doi: 10.2147/IJN.S194304

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© 2019 Wang et al.

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Apoptotic effects to A549 cells. (A) Apoptosis determined by flow cytometry, (B) The proportion of apoptosis after varying liposomal formulations treatment. Data are presented as mean ± SD (n=3). a. Blank control; b. Dioscin liposomes; c. Daunorubicin liposomes; d. Daunorubicin and dioscin codelivery liposomes; e. Targeted daunorubicin and dioscin codelivery liposomes. 1, vs a; 2, vs b; 3, vs c; 4, vs d. p<0.05. (C) Fluorescence microscopy images of intracellular ROS level in A549 cells.

Abbreviation: ROS, reactive oxygen species.