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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Bone. 2019 Mar 23;124:14–21. doi: 10.1016/j.bone.2019.03.029

Table 2.

Results from laboratory evaluation of bone markers in siblings with biallelic, pathogenic B4GALT7 variants.

Male Sibling Female Sibling Reference Range
Serum
Calcium (mg/dl) 10.1 9.8 M: 9.4–10.325
F: 9.4–10.825
Calcium, ionized (mg/dL) 5.08 5.03 M: 4.6–5.325
F: 4.9–5.325
Phosphorus (mg/dL) 5.2 5.1 M: 3.6–5.825
F: 4.5–6.525
%CK-BB (Brain-type creatine kinase) (IU/L) 2 2 5–2526
Alkaline phosphatase (U/L) 289 390 M: 60–45025
F: 100–35025
Bone alkaline phoshatase (mcg/L) 95 142 M: 51–16427
F: 147–35927
Parathyroid hormone (PTH) (pg/mL) 26 32 9–5228
25-OH vitamin D (ng/mL) 47 41 21–10029
Creatine kinase (U/L) 160 276 M: 55–21530
F: 75–23030
Urine (spot)
Calcium/creatinine ratio 0.12 0.23 M: 0.04–0.725
F: 0.05–1.125
Phosphorus/creatinine ratio 0.24 0.33 M: 0.8–3.225
F: 1.2–1825
Bone Turnover Markers
Serum osteocalcin (ng/ml) 122 136 M: 56–8031
F: 66–8831
Urine NTX-telopeptide (nmol/mmol creatinine) 598 628 M: 386–68132
F: 646–92332