Table 1.
Particle size, PDI and appearance stability of SCZ-NEs with different O:S ratios
| Formulations | Capryol 90 (%) | Smix (%) (Km=2:1) | Aqueous (%) | Particle size (nm) | PDI | Appearance |
|---|---|---|---|---|---|---|
| NE1 | 5 | 45 | 50 | 54.2±3.4 | 0.205±0.02 | Limpid |
| NE2 | 10 | 40 | 50 | 86.5±5.7 | 0.256±0.07 | Limpid |
| NE3 | 15 | 35 | 50 | 154±11.2 | 0.353±0.06 | Limpid |
| NE4 | 20 | 30 | 50 | 236±15.6 | 0.523±0.12 | Turbid |
| NE5 | 25 | 25 | 50 | 315±19.3 | 0.696±0.14 | Turbid |
Note: Results are represented as mean±SD (n=3).
Abbreviations: PDI, polydispersity index; O:S, oil/mixed-surfactant; SCZ-NEs, sulconazole-loaded in nanoemulsions; Smix, mixed-surfactant; km, surfactant:co-surfactant ratio.