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. 2019 May 28;14:3955–3966. doi: 10.2147/IJN.S206657

Table 3.

Range of variables and their levels used in CCD

Independent variables Unit Code level
−1.41 −1 0 1 1.41
Oil/mixed-surfactants ratio w/w 1/9 1/8 1/6 1/4 1/3
Proportion of aqueous
phase
% 50 55 60 65 70

Note: Optimization experiment was constructed by 2 factors and 5 levels.

Abbreviation: CCD, central composite design.