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. Author manuscript; available in PMC: 2020 Jan 17.
Published in final edited form as: Mol Cell. 2018 Dec 6;73(2):291–303.e6. doi: 10.1016/j.molcel.2018.10.038

Figure 6. Mael represses transposons by piRNA-dependent and piRNA-independent mechanisms.

Figure 6.

(A) Scatter plots comparing sense steady-state RNA (RNA-seq) abundance between maelM391/r20 and piwi2/Nt ovaries. All data are the mean of six independent biological samples for uniquely mapping reads.

(B) H3K4me3 ChIP-seq data from 5 kb up and downstream of the 5′ ends of the individual transposon insertions with increased steady-state mRNA levels in maelM391/r20 compared to piwi2/Nt ovaries (110 within clusters and 324 outside clusters from Figure 6A). Individual control and maelM391/r20 replicates are shown and mean H3K4me3 signal surrounding the 5′ ends is shown above, while signal from individual transposon insertions is show below.