Table 1.
Baseline characteristics according to long- and short-acting ESA users
| Characteristic | No. of Missing Value (%) | Total, |
Long-Acting ESA Users |
Short-Acting ESA Users |
Standardized Difference |
|---|---|---|---|---|---|
| n=194,698 | n=124,067 | n=70,631 | |||
| Age, yr | 5 (<0.1) | 67.5 (12.4) | 67.7 (12.3) | 67.2 (12.5) | 0.04 |
| Men, % | 0 | 61.6 | 61.6 | 61.5 | 0.002 |
| Body mass index, kg/m2 | 16,822 (8.6) | 22.3 (4.2) | 22.2 (4.2) | 22.3 (4.3) | 0.02 |
| HD vintage, yr | 41 (<0.1) | 6 [3–11] | 6 [3–11] | 6 [3–11] | 0.01 |
| HD duration, h/wk | 1349 (0.7) | 11.7 (1.8) | 11.7 (1.8) | 11.8 (1.8) | 0.06 |
| Single-pool Kt/V | 11,129 (5.7) | 1.43 (0.32) | 1.43 (0.32) | 1.43 (0.32) | 0.02 |
| Predialysis sBP, mm Hg | 9298 (4.8) | 152.1 (24.0) | 152.1 (24.1) | 152.1 (23.8) | 0.001 |
| Predialysis dBP, mm Hg | 9577 (4.9) | 77.6 (14.4) | 77.5 (14.5) | 77.7 (14.4) | 0.01 |
| Urea nitrogen, mg/dl | 1299 (0.7) | 61.9 (16.1) | 61.8 (16.2) | 62.1 (15.8) | 0.02 |
| Albumin, g/dl | 3886 (2.0) | 3.63 (0.58) | 3.61 (0.65) | 3.66 (0.42) | 0.09 |
| CRP, mg/dl | 31,955 (16.4) | 0.1 [0.1–0.4] | 0.1 [0.1–0.5] | 0.1 [0.1–0.4] | 0.06 |
| Albumin-adjusted Ca, mg/dl | 1389 (0.7) | 9.22 (0.75) | 9.22 (0.75) | 9.23 (0.75) | 0.009 |
| Phosphate, mg/dl | 1477 (0.8) | 5.17 (1.44) | 5.18 (1.45) | 5.15 (1.42) | 0.02 |
| Intact PTH, pg/ml | 13,236 (6.8) | 125 [66–205] | 125 [66–205] | 126 [66–206] | 0.002 |
| Hemoglobin, g/dl | 2366 (1.2) | 10.5 (1.2) | 10.5 (1.2) | 10.5 (1.1) | 0.02 |
| Ferritin, ng/ml | 18,121 (9.3) | 80 [34–169] | 77 [33–163] | 86 [36–179] | 0.05 |
| TSAT, % | 44,246 (22.7) | 26.5 (24.3) | 26.7 (26.7) | 26.2 (19.3) | 0.02 |
| Diabetes mellitus, % | 0 | 37.9 | 38.0 | 37.9 | 0.002 |
| Past history of MI, % | 23,115 (11.9) | 9.2 | 9.2 | 9.1 | 0.004 |
| Past history of CH, % | 23,672 (12.2) | 5.7 | 5.7 | 5.7 | 0.002 |
| Past history of CI, % | 21,867 (11.2) | 17.9 | 17.8 | 18.0 | 0.003 |
| Past history of amputation, % | 22,802 (11.7) | 3.3 | 3.5 | 3.1 | 0.02 |
Data presented as mean (SD) or median [interquartile range]. Standardized difference of <0.1 denotes a negligible difference between groups. HD, hemodialysis; sBP, systolic BP; dBP, diastolic BP; Ca, calcium; TSAT, transferrin saturation; MI, myocardial infarction; CH, cerebral hemorrhage; CI, cerebral infarction.