Table 2.
Characteristics of colonic polyps in screen positive participants who underwent work-up colonoscopy (n=223)
| Characteristics | All | CKD Stages 3–5 | Dialysis | Transplant | P Valuea |
|---|---|---|---|---|---|
| Participants with polyps | 223 (100) | 95 (42.6) | 66 (29.6) | 62 (27.8) | 0.03 |
| Polyps per patientb | |||||
| 1 polyp | 83 (37.2) | 34 (35.8) | 17 (25.8) | 32 (51.6) | 0.01 |
| 2–3 polyps | 90 (40.4) | 38 (40.0) | 29 (43.9) | 23 (37.1) | 0.7 |
| >3 polyps | 50 (22.4) | 23 (24.2) | 20 (30.3) | 7 (11.3) | 0.03 |
| Location of the largest polyp | |||||
| Cecum | 36 (16.1) | 23 (24.2) | 4 (6.1) | 9 (14.5) | 0.01 |
| Ascending colon | 35 (15.7) | 18 (18.9) | 11 (16.7) | 6 (9.7) | 0.3 |
| Transverse colon | 33 (14.8) | 9 (9.5) | 17 (25.8) | 7 (11.3) | 0.01 |
| Descending colon | 22 (9.9) | 7 (7.4) | 9 (13.6) | 6 (9.7) | 0.4 |
| Sigmoid colon/rectum | 95 (42.6) | 37 (38.9) | 24 (36.4) | 34 (54.8) | 0.07 |
| Other | 2 (0.9) | 1 (1.1) | 1 (1.5) | 0 | 0.6 |
| Size of the largest polyp, mm | |||||
| <5 | 40 (17.9) | 17 (17.9) | 10 (15.2) | 13 (21.0) | 0.7 |
| 5–10 | 124 (55.6) | 53 (55.8) | 39 (59.1) | 32 (51.6) | 0.7 |
| >10 | 59 (26.5) | 25 (26.3) | 17 (25.8) | 17 (27.4) | 0.9 |
| Neoplastic lesionsc | |||||
| Tubulovillous adenomas | 62 (27.8) | 30 (31.6) | 16 (24.2) | 16 (25.8) | 0.5 |
| Tubular adenomas | 149 (66.8) | 62 (65.3) | 46 (69.7) | 41 (66.1) | 0.8 |
| Villous adenomas | 3 (1.3) | 2 (2.1) | 0 | 1 (1.6) | 0.5 |
| Sessile serrated adenomas/polyps | 10 (4.5) | 6 (6.3) | 1 (1.5) | 3 (4.8) | 0.6 |
| Non-neoplastic lesionsc | |||||
| Inflammatory polyps | 7 (3.1) | 1 (1.1) | 3 (4.5) | 3 (4.8) | 0.3 |
| Hyperplastic/others | 44 (19.7) | 16 (16.8) | 18 (27.3) | 10 (16.1) | 0.5 |
| Advanced neoplasiab | 103 (46.1) | 44 (46.3) | 31 (47.0) | 28 (45.2) | 0.9 |
| Colorectal cancers | 7 (3.1) | 2 (2.1) | 3 (4.5) | 2 (3.2) | 0.7 |
a
P values are on the basis of chi-square analyses for comparison between the three groups (CKD stages) in each row.
b
Advanced colorectal neoplasia was defined as any colorectal adenoma with at least one of the following features: ≥1 cm in size, villous component (≥25%) or high-grade dysplasia; or any serrated lesion ≥1 cm in diameter, or with dysplastic component; or any invasive colorectal cancer.
c
Participants can have more than one of the neoplastic and non-neoplastic lesions.