Table 2.

Glomerular morphometric measures at baseline and follow-up biopsies

Structural Measurement	Baseline	Follow-Up	P Value
GBM width, nm	440±78	528±130	<0.001
Vv(Mes/glom)	0.25±0.05	0.30±0.08	<0.001
Sv(PGBM/glom), µm2/µm3	0.10±0.02	0.09±0.02	<0.001
Mean glomerular volume, 106 µm3a	2.47±0.64	2.76±1.00	0.063
Total glomerular filtration area, 105 µm2a	0.25±0.09	0.22±0.07	0.05
Podocyte volume, µm3	1275±627	814±618	<0.001
Vv(PC/glom)	0.16±0.04	0.08±0.03	<0.001
Podocyte number density per glomerulus, 106 µm3	151±82	171±162	0.44
Percentage of sclerosed glomeruli, %b	0 (0–3)	10 (3–19)	<0.001c

Data are mean±SD for continuous measures and numbers with percentages for categorical variables. Missing measures because of insufficient tissue for measurement at first and/or second biopsy. n=48.

^an=33.

^bn=32.

^cP value from paired t test except Kruskal–Wallis test.