Table 2.
Spearman Partial Correlation Coefficients of Regional Diffusion Tensor Tractography Microstructure with Injury Severity for Traumatic Brain and Extracranial Injury Groups
| Traumatic brain injury (n = 53) | ||||
|---|---|---|---|---|
| Diffusion tensor tractography metrics | Admission GCS Score df (49) | Modified Injury Severity Score df (49) | Extracranial injury (n = 26) Modified Injury Severity Score df (22) | |
| Pathway fractional anisotropy | r (p) | r (p) | r (p) | |
| Origin | Termination | |||
| Left hemisphere | ||||
| Amygdala | ||||
| oPFC | 0.108 (0.450) | −0.162 (0.257) | −0.006 (0.978) | |
| rACB | 0.464 (0.001) | 0.001 (0.996) | 0.168 (0.433) | |
| Hippocampus | ||||
| Amygdala | 0.155 (0.277) | −0.169 (0.236) | −0.033 (0.113) | |
| oPFC | 0.208 (0.144) | 0.103 (0.470) | 0.263 (0.214) | |
| Right hemisphere | ||||
| Amygdala | ||||
| oPFC | 0.294 (0.036) | 0.156 (0.275) | −0.041 (0.850) | |
| rACB | 0.102 (0.477) | 0.012 (0.931) | 0.081 (0.706) | |
| Hippocampus | ||||
| Amygdala | −0.113 (.430) | 0.131 (0.358) | −0.018 (0.933) | |
| oPFC | 0.348 (0.012) | −0.141 (0.325) | 0.520 (0.009) | |
| Gray matter mean diffusivity | ||||
| Left hemisphere | ||||
| Amygdala | −0.362 (0.009) | 0.038 (0.793) | 0.133 (0.534) | |
| Hippocampus | −0.278 (0.048) | 0.223 (0.116) | 0.156 (0.468) | |
| hight Hemisphere | ||||
| Amygdala | −0.235 (0.097) | 0.227 (0.109) | −0.100 (0.642) | |
| Hippocampus | −0.425 (0.002) | 0.132 (0.357) | 0.181 (0.397) | |
GCS, Glasgow Coma Scale; oPFC, orbital prefrontal cortex; rACB, rostral anterior cingulate bundle.
Note: Age at scan and scanner upgrade partialled.