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HU-910 increased cortical synaptogenesis 25 days after injury. Extraction of proteins from the cytosolic fraction prepared from cortical tissue adjacent to the site of injury was analyzed by Western blot, the levels of synaptophysin (SYP) was quantified, and a 2-fold increase in SYP levels was found after drug treatment (n = 4–5/group). **p < 0.001 vs. vehicle-treated mice.
