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. 2019 May 22;36(11):1890–1907. doi: 10.1089/neu.2018.6107

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Copyright 2019, Mary Ann Liebert, Inc., publishers

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FIG. 10. — Generalized electroencephalographic seizure in a rat with traumatic brain injury. Upper panel: Electroencephalogram (EEG; 30-sec epoch, low-frequency filter 0.5 Hz, high-frequency filter 100 Hz) showing a generalized electroencephalographic seizure after lateral fluid-percussion injury–induced impact. Seizure duration was 130 sec. Note the frequency evolution, changing morphology and modulation of the activity, culminating in attenuation. Video recording indicated slight head-turning to the left. Seizure beginning and ending are marked with a black box. Lower panel: A heat map representing 12 h of continuous EEG in the same rat. Orange box indicates the seizure in upper panel. Note that the animal had 13 seizures within 12 h. On the heat map, each seizure is identifiable by a peak in power. For a video-EEG showing a non-convulsive seizure in a rat with TBI, see Supplementary Video S4. Color image is available online.