Figure 7.

Hippocampus staining for GFAP, UCH-L1, and MMP-9 in each group.

We can note trend to less intensive GFAP immunostaining in the hippocampus (dentate gyrus + CA-1 region) after HH and TBI+HH compared with TBI alone. For UCH-L1 and MMP-9, immunostaining is more pronounced for HH and TBI+HH groups compared with Sham and TBI alone groups. GFAP indicates glial fibrillary acidic protein; HH, hypoxia/hypotension group; MMP-9, matrix metalloproteinase 9; Sham, Sham group; TBI, traumatic brain injury group; TBI+HH, traumatic brain injury and hypoxia/hypotension group; UCH-L1, ubiquitin carboxy-terminal hydrolase-L1.