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. 2019 Mar 5;244(8):621–629. doi: 10.1177/1535370219833624

Figure 3.

Figure 3.

The list of Bax inhibitors explained in this article. This figure shows the multiple steps of Bax activation mechanism, and the points of regulation by these inhibitors. Anti-apoptotic members of Bcl-2 family of proteins (Bcl-2, Bcl-X, and Mcl-1) are known to inhibit mitochondrial translocation and dimerization of Bax. (A color version of this figure is available in the online journal.)1,2