Figure 10.

Expression profile of TXNDC5 in human normal tissue and lung cancer. A and B, anti-TXNDC5 staining (brown) with counterstaining by hematoxylin (blue) was performed on tissue microarray slides of human normal organs (A) and lung normal and lung tumor specimens from patients (B). C, quantitative data from tissue microarray were shown. * p < 0.05 (t test), compared with normal lung. D, an example data set from Oncomine indicates amplified DNA copy numbers in human lung cancer. E and F, Kaplan–Meier Plotter analysis of the TCGA data set in human lung cancer indicates the negative association of Srx with patient survival (E) and the positive association of TXNDC5 with patient survival (F). G, a proposed model of Srx and TXNDC5 in lung cancer and their value as potential biomarkers to predict patient survival. Error bars, S.D.