. Author manuscript; available in PMC: 2019 Jun 6.

Published in final edited form as: Angew Chem Int Ed Engl. 2016 Aug 31;55(40):12382–12386. doi: 10.1002/anie.201605214

Table 1:

Characterization of transfection agents and polyplexes corresponding to optimal transfection efficacy.

Transfection Agent^[a]	MM^[b] [kDa]	Charge ratio^[c]	D_H [nm]	ζ potentia [mV]
PEI	25	50:1	490±60	40±10
PEI(Pep)	166	8:1	425±100	65±5
PEI(Mo)	164	20:1	400±110	60±6
PMAS(Pep)	53	5.5:1	140±60	27±8
PMAS(Mo)	53	5.5:1	215±25	43±6

^[a]

Polyplexes of polymers tested at the loadings noted in Figure 5.

^[b]

Molecular mass of transfection agent, calculated based on commercial linear PEI; for PMAS(R) materials, PMAS was measured by SEC using PS standards of narrow dispersity, then calculated for the corresponding TAC group.

^[c]

Ratio of either N to phosphate anions (PEI) or TAC to phosphate anions.