Table 2.

Association Between Serotonin_1A BP_F in 12 ROIs and Lethality of Follow-up Suicide Attempts^a

Log-Transformed PBF per ROI	With Zero-Lethality Attempters				Without Zero-Lethality Attempters
	Estimate	t Value	P Value	Adjustedb	Estimate	t Value	P Value	Adjustedb
RN	0.08	2.88	.01	NA	0.12	4.43	.002	NA
Amygdala	0.01	0.48	.64	0.64	0.02	0.68	.51	0.51
Hippocampus	0.05	1.61	.13	0.15	0.07	1.82	.10	0.11
Parahippocampal gyrus	0.05	1.65	.12	0.15	0.07	2.13	.06	0.08
Temporal lobe	0.05	1.64	.12	0.15	0.08	2.13	.06	0.08
Anterior cingulate gyrus	0.06	1.79	.09	0.15	0.09	2.27	.04	0.08
Dorsal PFC	0.07	1.84	.09	0.15	0.10	2.44	.03	0.08
Medial PFC	0.06	1.65	.12	0.15	0.09	2.05	.07	0.08
Orbital PFC	0.05	1.56	.14	0.15	0.09	2.13	.06	0.08
Insula	0.05	2.31	.04	0.15	0.07	2.41	.04	0.08
Occipital lobe	0.05	1.71	.11	0.15	0.09	2.17	.05	0.08
Parietal lobe	0.06	1.71	.11	0.15	0.09	2.24	.05	0.08

Abbreviations: BP_F, binding potential; NA, not applicable in primary analysis; PFC, prefrontal cortex; RN, raphe nuclei; ROI, region of interest.

^aPatients underwent imaging with carbon 11-labeled 3-amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile ([¹¹C]DASB).

^bSignificance levels for exploratory analyses are adjusted using the Benjamini-Hochberg method.