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. Author manuscript; available in PMC: 2019 Jun 6.
Published in final edited form as: Mol Nutr Food Res. 2018 Jul 19;62(18):e1800228. doi: 10.1002/mnfr.201800228

Table 2.

Cytotoxicity of SFN analogs in HCT116 colon cancer cell line (confluent cell density).

graphic file with name nihms-1018842-t0018.jpg
 Cell viability of HCT116
cells IC50 [μm]
(mean ± SE)
Compound ID R n Confluent cell density
8D graphic file with name nihms-1018842-t0019.jpg 1 10.6 ± 2.2a)
3D 0 12.3 ± 3.3a)
9D 2 11.5 ± 4.3a)
9C graphic file with name nihms-1018842-t0020.jpg 2 14.9 ± 7.9
9A graphic file with name nihms-1018842-t0021.jpg 2 18.2 ± 5.2
8E graphic file with name nihms-1018842-t0022.jpg 1 30.1 ± 4.1
8B graphic file with name nihms-1018842-t0023.jpg 1 36.6 ± 7.5
9B 2 56.5 ± 3.5
SFN2 methyl 2 54.5 ± 5.5
SFN methyl 1 56.4 ± 1.8
a)

p < 0.05 compared to SFN.