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Cytotoxicity of SFN analogs in cancer (SW480) versus normal (CCD112) colon cells.
 |
Cell viability IC50
[μm] (mean ± SE) |
|||
|---|---|---|---|---|
| Compound ID | R | n | Colon cancer SW480 |
Colon normal CCD112 |
| 8D |  |
1 | 5.0 ± 0.9a) | >60 |
| 3D | 0 | 16.2 ± 2.6 | >60 | |
| 9D | 2 | 23.1 ± 5.8 | >60 | |
| SFN | Methyl | 1 | 45.1 ± 10.9 | >60 |
p < 0.01 compared to SFN.
