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. 2019 May 22;11(6):1573–1585. doi: 10.1093/gbe/evz101

Table 2.

PSGs from the Single-Branch Foreground Analysesa

Foreground Branch Ensembl ID Gene Symbol Adjusted P Value (P < 0.05) Foreground ω Biochemical Pathway or Gene Function Information
Aglaeactis castelnaudii 11922 JPH1 0 7.53 Part of structural foundation and cross-talk across cell membrane in skeletal muscle
Amazilia amazilia 02317 MDH1 0.017 2.37 Glucose metabolism, Krebs cycle
Amazilia viridicauda 01501 DNAJA1 0.012 281.75 Heat shock protein cochaperone; regulation of apoptosis in response to cellular stress
Amazilia viridicauda 08371 NOB1 0.003 139.67 rRNA processing in the nucleus and cytosol
Chaetocercus mulsant 00167 CACTIN 0.017 34.35 Regulation of innate immune response
Chaetocercus mulsant 18304 COX1 0 1.00021 Respiratory electron transport, oxidative phosphorylation
Chaetocercus mulsant 18150 FEM1A 0 619.67 Substrate recognition; anti-inflammatory signaling
Chaetocercus mulsant 13770 NDUFB4 0.038 108.64 Respiratory electron transport, oxidative phosphorylation
Coeligena violifer 05988 ATG9A 0.007 17.95 Related to autophagy
Coeligena violifer 06887 NDUFB10 0.008 5.91 Respiratory electron transport, oxidative phosphorylation
Colibri coruscans 05988 ATG9A 0.008 22.73 Related to autophagy
Colibri coruscans 13977 CLPB 0 8.61 Longevity regulating pathway; diverse cellular activities
Patagona gigas peruviana 18302 ND1 0 15.53 Respiratory electron transport, oxidative phosphorylation
Phaethornis malaris 11919 ATP6V1D 0.018 1.34 Respiratory electron transport, oxidative phosphorylation; insulin receptor recycling; innate immune system
Phaethornis malaris 11555 MLF1 0.016 13.71 Transcriptional misregulation in cancer
Phlogophilus harterti 08535 MFGE8 0.036 1.13 Metabolism of proteins; promotes phagocytosis of apoptotic cells; immune function
Phlogophilus harterti 06887 NDUFB10 0.003 780.9 Respiratory electron transport, oxidative phosphorylation
Phlogophilus harterti 08539 SDHA 0.04 1.09 Respiratory electron transport, oxidative phosphorylation; Krebs cycle
a

Ensembl IDs begin with prefix ENSTGUP000000. The associated foreground branch omega (ω) values are shown for two site classes. For these site classes, the foreground branches are both evolving under positive selection (ω > 1), but the background branches are either evolving neutrally (ω = 1) or under purifying selection (ω < 1). Genes with foreground ω values just above one should be interpreted with caution, as they may represent positive selection or relaxed purifying selection. Pathway or gene function information was compiled from the Panther and Genecards databases.