Skip to main content
. 2019 May 22;11(6):1573–1585. doi: 10.1093/gbe/evz101

Table 3.

Summary of All Codeml Results for Shared Pathways, PSGs, and/or Positively Selected Sites for High-Elevation Species >2,500 m (Colibri coruscans, Aglaeactis castelnaudii, Coeligena violifer, Metallura phoebe, and Patagona gigas peruviana)a

Species Shared Pathway/Gene Function under Selection Shared PSG Unique PSG Shared Positively Selected Site
C. violifer Related to autophagy ATG9A
Col. coruscans
C. violifer Respiratory electron transport, ATP synthesis, metabolism NDUFB10
P. gigas peruviana ND1
High-elevation species >2,500 m Regulation of the cell cycle CCNI Asp80
Formation of fibrin clot (clotting cascade) C1QBP Ala60
Mitochondrial translation; organelle biogenesis and maintenance MRPS26 Val275
Respiratory electron transport, oxidative phosphorylation UQCRQ Gly3, Ser4
Metabolism of proteins; mitochondrial protein import TIMM17A Lys1, Asp2, Lys3
Negative regulation of angiotensin II (causes vasoconstriction and increase in blood pressure) signaling AGTRAP
a

From left to right, the table shows the group of species that share pathways, PSGs, and positively selected sites (yes–yes–yes), share pathways and PSGs but not sites (yes–yes–no), and that have different PSGs involved in similar pathways/functions (yes–no–no). For shared sites, we show the reference amino acid (first sequence in alignment) and site position, otherwise a dash is shown if no positively selected sites were identified or shared.