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. 2018 Oct 10;11(10):e006059. doi: 10.1161/CIRCEP.117.006059

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© 2018 The Authors.

Circulation: Arrhythmia and Electrophysiology is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 7. — Collagen content in Sham and repaired tetralogy of Fallot (rTOF) left ventricles (LVs). A, Representative histological sections of Sham and rTOF LVs stained with Masson trichrome. In addition to diffuse fibrosis, large fibrotic regions are visible in the LV base and apex of rTOF pigs. B, Collagen content, expressed as a percentage of total section area, was increased in rTOF LV base and apex compared with Sham. C, A positive correlation was found between LV collagen content and right ventricular end-diastolic volume indexed to body surface area (RV-EDVi), and (D) a negative correlation was found between RV-EDVi and LV longitudinal conduction velocity (CV_L). Data are means±SD. Sham, n=4; rTOF, n=4. **P<0.01, ***P<0.001.