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. 2019 Apr 16;212(2):523–535. doi: 10.1534/genetics.119.301795

Figure 6.

Figure 6

timp-1 and cri-2 partially suppress the gonadal morphogenesis defects in the gon-1/ADAMTS mutants. (A–F) DIC images of posterior gonads of gon-1(e1254);control(RNAi) (A), gon-1(e1254);timp-1(RNAi) (B), gon-1(e1254);cri-2(RNAi) (C), gon-1(q518) (D), gon-1(q518);timp-1(tk71)/+ (E), and gon-1(q518);cri-2(gk314) (F). (G) Percentages of abnormal gonad morphology in the young adults. The arrowheads in the panels indicate vulvae. The orange dotted lines outline the gonads in the panels. The four classes of gonadal defects were scored as in Figure 2K. P-values are indicated for Fisher’s exact test in comparison with gon-1 (e1254);control(RNAi), gon-1 (e1254), gon-1(q518);control(RNAi), or gon-1(q518). * P < 0.05, *** P < 0.005. In all panels, the anterior region of the gonad is to the left and its dorsal region is at the top of the image. Bar, 10 μm. The animals were cultured at 20° except for those used in the RNAi experiments (24.5°). RNAi, RNA interference.