Suppression effects of timp-1 and cri-2 on mig-17 and gon-1 null mutants are abrogated by overexpression of gon-1 or mig-17::Venus, respectively (A and B). Percentages of abnormal gonad morphology in young adults. The four classes of gonadal defects were scored as in Figure 2K. P-values are indicated for Fisher’s exact test in comparison with mig-17(k174);control(RNAi);Ex[gon-1p::gon-1], mig-17(k174) Ex[gon-1p::gon-1], gon-1(q518);control(RNAi);Ex[mig-17p::mig-17::Venus], or gon-1(q518);Ex[mig-17p::mig-17::Venus]. The animals were cultured at 20° except for those used in the RNAi experiments (24.5°). NS, not significant; RNAi, RNA interference.