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. 2019 Apr 26;212(2):469–487. doi: 10.1534/genetics.119.302232

Figure 1.

Figure 1

Schematic organization of the pseudoautosomal region (PAR) in human and the house mouse. (A) Synteny map of the human and mouse X chromosomes. Orthologous genes are shown in black, nonorthologous genes in gray, and the gene marking the end of the human–mouse synteny block (MID1) in red. PARs shown as gray boxes. Not all human genes are shown. (B) The mouse PAR. The canonical PAR defined in the C57BL/6J reference strain (top) encompasses at least two genetically mapped protein-coding genes (Sts and Asmt) and the 3′ fragment of Mid1. Its physical size is ∼750 kb, most of which consists of unassembled repetitive sequence. The extended PAR of CAST/EiJ (bottom) involves the duplication of ∼400 kb of ancestrally X-unique sequence onto the Y, including the 5′ fragment of Mid1 (White et al. 2012a).