Age of neoplasm diagnosis and neoplasm type for the 116 DICER1 carriers (151 neoplasms; proband and nonproband) from all three studies. Specific DICER1-associated neoplasms are highlighted in color: type I pleuropulmonary blastoma (PPB; red), type II PPB (green), type III PPB (orange), Sertoli-Leydig cell tumor (SLCT; purple), and cystic nephroma (gray). Diagnoses to (A) age 10 years and (B) age 60 years. Gray boxes span from the first to the third quartile of observed diagnoses, and vertical bars in the boxes indicate median diagnosis age. NCMH, nasal chondromesenchymal hamartoma.