Table 2.

Amino acid comparison of Semliki Forest complex members based on E2 glycoprotein

	E2
	CHIKV	ONNV	SAGV	GETV	SFV	RRV	BEBV	MAYV	UNAV
CHIKV	-	82	54	54	57	57	56	55	55
ONNV	91	-	54	54	57	56	55	56	55
SAGV	70	71	-	98	68	80	66	61	63
GETV	70	71	98	-	68	80	66	61	63
SFV	72	72	82	82	-	69	69	65	65
RRV	70	70	90	91	83	-	67	61	64
BEBV	71	71	80	80	82	79	-	62	62
MAYV	70	72	76	76	80	76	76	-	64
UNAV	69	70	78	78	81	78	78	79	-

	Domain A
	CHIKV	ONNV	SAGV	GETV	SFV	RRV	BEBV	MAYV	UNAV
CHIKV	-	87	49	48	57	53	51	52	56
ONNV	93	-	48	48	57	53	49	55	56
SAGV	69	70	-	97	59	74	57	51	56
GETV	68	69	97	-	58	75	58	52	56
SFV	66	69	76	75	-	59	65	64	61
RRV	67	68	86	88	78	-	59	51	57
BEBV	67	67	75	75	79	74	-	59	59
MAYV	72	74	74	74	81	73	76	-	63
UNAV	70	70	75	76	82	74	82	84	-

	Domain B
	CHIKV	ONNV	SAGV	GETV	SFV	RRV	BEBV	MAYV	UNAV
CHIKV	-	80	63	64	61	66	66	68	63
ONNV	86	-	58	59	56	61	58	56	61
SAGV	76	73	-	98	75	83	73	66	70
GETV	78	75	98	-	76	85	71	68	71
SFV	80	75	83	85	-	71	70	61	63
RRV	81	76	90	92	83	-	70	68	70
BEBV	78	75	81	80	81	81	-	63	56
MAYV	80	73	85	86	85	86	76	-	66
UNAV	75	71	76	78	75	81	71	81	-

BEBV = Bebaru virus; CHIKV = chikungunya virus; GETV = Getah virus; MAYV = Mayaro virus; ONNV = o’nyong’nyong virus; RRV = Ross River virus; SAGV = Sagiyama virus; SFV = Semliki Forest virus; Una = UNAV virus. Percent amino acid identity is shown above the diagonal in black. Percent amino acid similarity is shown below the diagonal in grey.